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Acriflavin Inhibits the Proliferation of Trypanosoma musculi
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165 b
30 dni na zwrot towaru
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In Africa, it is estimated that trypanosomiasis§occurs in more than 37 Sub-Saharan countries covering§more than a third of Africa s total area. The§infection threatens an estimated 60 million people§and about 50 million cattle. According to the World§Health Organization (WHO, 2002), estimation about§500,000 new cases of human infection and 3 million§deaths in cattle occur every year. The economic§losses in cattle production alone are estimated to be§about 1.2 billion U.S dollars a year. If this figure§were extrapolated to the whole tsetse infested land,§the total losses in terms of agricultural Gross§Domestic Product, would amount to $ 4.75 billion§dollars per year (WHO, 2002). As of now, there is no§efficient and safe enough drug to be used as the§first-line drug to fight trypanosomiasis (Jarvinen§and Dalmasso, 1977; Fong et al., 1984; Odeika et al.,§1994; Obexer et al., 1995; Gubler, 1998; Klingbeil§and Englund, 2004). The urgent need for more§selective and less toxic antitrypanosomiasis drug has§stimulated this study of acriflavine as a possible§antitrypanosomial drug.
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