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Wine has a long recorded history that goes back more than 7.5 thousand years. The earliest suspected wine residues come from the early to mid-fifth millennium b.c - Hajji Firuz Tepe, in the northern Zagros Mountains of Iran. More information and historical data indicate the existence of wine in antiquity dating back to the Stone Age, about 6000 years ago, in Mesopotamia and Egypt, which symbolized the blood of Christ and Christianity. Historically wine has been associated with celebrations and cults as well as a tranquilizer for the human spirit. Indeed Hippocrates, father of the medicine, used wine as an integral part of his medications and recommended its use as a diuretic and general antiseptic. Gender Vitis and its 700 different kind of species in particular Vitis vinifera of interest for wine producers. Vitis vinifera originated from the south of the Black Sea where it is cultivated by Transcaucasia. For the first time the cultivation of grapes is mentioned in the Bible (Genesis IX, xviii). Since its first appearance reported in the south of the Caucasus Mountains, the vine cultivation and wine production was spread down into Egypt.