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This book constitutes the thoroughly refereed post-conference proceedings of the 6th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2013, held in Barcelona, Spain, in February 2013. The 28 revised full papers presented were carefully reviewed and selected from a total of 392 submissions. The papers cover a wide range of topics and are organized in four general topical sections on biomedical electronics and devices; bioinformatics models, methods and algorithms; bio-inspired systems and signal processing; health informatics.