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Abstract Psychological effects of breast cancer during treatment were evaluated. For this purpose primary and secondary data was record from Bahawalpur Institute of Nuclear Medicines and Oncology (BINO). The data regarding the psychological effects of breast cancer (Primary data) was recorded from the patients who visited the BINO for the treatment of breast cancer. In this regard 200 patients (100 during treatment + 100 after treatment) were evaluated through a questionnaire which was developed with the help of Psychologists and Staticians. The results of the present study concluded that the patients involved in CA breast cancer undergo several psychological effects. During the treatment of CA breast, patients psychological treatment is must to boost the self esteem and courage of the patient to fight against the disease.