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This is comprehensive textbook of general pediatrics. Chapters begin with a case, followed by medical information with a clinically focused emphasis. The content contains the basis for a general pediatrics residency curriculum. Medical students can use this as a reference for clinically important aspects of the chapter topics. This textbook is a project of the University of Hawaii John A. Burns School of Medicine Department of Pediatrics, to give our faculty and other interested authors, an academic contribution opportunity. We thank who have taken the time and thoughtful consideration to provide the information contained in this textbook.