Circulatory and Developmental Aspects of Brain Metabolism

This monograph contains the Proceedings of the Second International Symposium on the Pathophysiology of Cerebral Energy Metabolism, organized and sponsored by the Serbian Academy of Sciences and Art, in Belgrade, September 16-20, 1979. The purpose of the SYmposium was to promote an inter disciplinary discussion on Circu1atory and Deve1oprnenta1 Aspects of Brain Metabolism. Doctors G. Buznikov (Moscow), I. Klatzo (Bethesda), B. B. Mrsulja (Belgrade) . O. Z. Se1inger (Ann Arbor), and M. Spatz (Bethesda) served as members of the Advisory Board, chaired by Dr. Lj. H. Raki6 (Belgrade) , and he1ped to plan the scientific pro gram. v CONTENTS 1 Opening Address S. Kanazir SECTION I CIRCULATORY ASPECTS Ischemia Related Changes in Adenine Nucleotide Metabolism . . . . . . . . 5 N. Murakami, W. D. Lust, F. A. M. de Azeredo and J. V. Passonneau Regional Glucose Metabolism and Nerve Cell Damage after Cerebral Ischemia in Normo- and Hypoglycemic Rats . . . . 23 N. H. Diemer and E. Siemkowicz Nuclear Cell Regulatory l1echanism in Cerebral Ischemia and Anoxia . . . . 33 T. Yanagihara Correlation of Amino Acid Concentrations, Permeability and Structural Changes in Monkey Brain Following Both Sustained and Transient Middle Cerebral Artery Occlusion . . 47 K. A. Conger and J . H. Garcia Histochemical and Biochemical Investigations on ATPase Activity Following Transient Brain Ischemia in Gerbils . . . .