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The topics addressed in this volume of comparative and veterinary pharmacology, as a series of succinct state of the art reviews, illustrate both the commonality and differences between drug pharmacodynamics and pharmacokinetics in animals and man and demonstrate the potential impact of drug use in animals on human health and the environment. Genetic modification of animals and the benefits this has brought to understanding human disease and the production of drugs for use in man is considered and the potential of new technologies for improving the treatment of animal disease explored.