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An in-depth study of bacilli has been encompassed in this profound book. Latest researches reflect that mycobacterium tuberculosis has a complex signaling expression, which enables its close interaction with the environment and one of its most significant properties is its capability to survive extended time periods under a non-replicative status. Although this feature is well characterized in other bacteria, the characteristically slow development rate of Mycobacterium Tuberculosis, along with a very thick and complex cell wall, make this pathogen particularly accustomed to the stress that is generated by the host against them. Reputed specialists have contributed comprehensive information regarding these specific properties of mycobacterium tuberculosis in this book.