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When we think of cancer in general terms, we are apt to conjure up a process characterized by a steady, remorseless and inexorable progress in which the disease is all conquering and none of the immunological and other defensive forces will help leading to faltering footsteps to the grave. Cervical cancer is the second most common cancer in women worldwide and represents 12% of all female malignancies. Enzymes are present in much higher concentration inside cells and are released into the systemic circulation as a result of tumor necrosis or a change in the membrane permeability of the cancer cells. Elevated enzyme levels may signal the presence of malignancy.As there are very few studies on enzyme markers in cervical cancer the present study has been undertaken to assess the reliability of some of the enzyme markers namely, serum adenosine deaminase (ADA) and gamma glutamyl transferase (GGT) which are inexpensive, analysed by easy methods and may be used as supportive parameters for diagnostic purpose and may add further for prognostic information.