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Aortic stenosis (AS) has become the most frequent valvedisease and has extensively been studied in recent years. Althoughgender differences have gained increasing attention in cardiolgy,little is known about gender differences in presentation andsurgical outcome of AS so far.In 408 consecutive pts. referred tosurgery because of symptomatic AS baseline clinical andechocardiographic data as well as outcome data were analyzed withregard to potential gender differences. At presentation, femalepts. were significantly older (73.7 ± 9.3 vs. 66.5 ± 11.5 years;p0,00001) and more symptomatic (NYHA class 2.3 ± 0.7 vs. 2.0 ±0.7; p0.0001). Overall survival as estimated by Kaplan Meieranalysis tended to be slightly better in women (89.1%, 86.6%, 76.3%versus 92.8%, 89.8%, 81.4% at 1-, 2- and 5 years) but thisdifference did not reach statistical significance (p=0.3). Furtherresearch must address whether differences in baselinecharacteristics are due to differences in disease onset andprogression or whether female patients get delayed medicalattention for some reasons.