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Although it is one of the most-widely studied viruses, many mysteries still remain about HIV. Covering the latest advances and challenges associated with clinical application of new antiviral drugs and vaccines, this revised edition is a companion to "Murad: HIV-1: Molecular Biology and Pathogenesis, 2E". Leading investigators in HIV research present a timely picture of the molecular mechanisms which guide HIV-1 expression and replication and provide the most current clinical strategies for combating this virus. It presents the latest developments in HIV-vaccine research. It describes new concepts in the discovery and design of novel anti-HIV drugs.