Immunological Tolerance and Accommodation

Immunological Tolerance and Accommodation provides the latest understanding of the cellular, molecular, and systematic regulation of immunological tolerance, an area that is of fundamental importance in immunology. For one hundred years, immunologists have struggled to understand how the immune system can attack with vigor and destroy foreign cells, microorganisms, and substances, all while sparing the immune individual from inadvertent injury. Research in various fields of immunology has revealed molecular, cellular, and systemic means by which tolerance and accommodation develop, but no line of research, review article, or published volume has coordinated the various findings and theories that have emerged. This book provides the only comprehensive and unified consideration on immunological tolerance and accommodation. Provides the only presentation that integrates molecular, cellular, and systemic mechanismsEffectively coordinates both basic and clinical subjectsAddresses both tolerance and accommodation, providing the best available resource for understanding how autoimmunity and autoimmune diseases are averted in most individuals Comprehensive and unified consideration of both tolerance and accommodation