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"Life is water dancing to the tune of macromolecules", statedAlbert Szent-Gyorgyi, medicine Nobel Prize winner in 1937. Proteinscan influence their hydration water dynamics and structure.Conversely water molecules can control the shape and function ofproteins and consequently also the cell biology and metabolism.Hydration dynamics can be a regulator for cell activity and caneven shut down cell metabolism completely under extreme conditions.The author shows that proteins and their hydration water moleculeshighly influence each other, their motions are coupled. The resultis a dynamic interplay, a dance to the same tune at terahertzfrequencies, of high importance to the cell and life ingeneral.